NMR Spectroscopy Explained: Simplified Theory, Applications and Examples for Organic Chemistry and Structural Biology

  • 15h 18m
  • Neil E. Jacobsen
  • John Wiley & Sons (US)
  • 2007

NMR Spectroscopy Explained : Simplified Theory, Applications and Examples for Organic Chemistry and Structural Biology provides a fresh, practical guide to NMR for both students and practitioners, in a clearly written and non-mathematical format. It gives the reader an intermediate level theoretical basis for understanding laboratory applications, developing concepts gradually within the context of examples and useful experiments.

  • Introduces students to modern NMR as applied to analysis of organic compounds.
  • Presents material in a clear, conversational style that is appealing to students.
  • Contains comprehensive coverage of how NMR experiments actually work.
  • Combines basic ideas with practical implementation of the spectrometer.
  • Provides an intermediate level theoretical basis for understanding laboratory experiments.
  • Develops concepts gradually within the context of examples and useful experiments.
  • Introduces the product operator formalism after introducing the simpler (but limited) vector model.

About the Author

Neil E. Jacobsen, PHD, is the NMR Facility Manager in the Department of Chemistry at the University of Arizona in Tucson, where he also teaches graduate-level NMR courses. He received his PhD in organic chemistry at the University of California-Berkeley and gained experience in protein NMR spectroscopy at the University of Washington and at Genentech, Inc.

In this Book

  • Fundamentals of NMR Spectroscopy in Liquids
  • Interpretation of Proton (1H) NMR Spectra
  • NMR Hardware and Software
  • Carbon-13 (13C) NMR Spectroscopy
  • NMR Relaxation—Inversion-Recovery and the Nuclear Overhauser Effect (NOE)
  • The Spin Echo and the Attached Proton Test (APT)
  • Coherence Transfer—INEPT and DEPT
  • Shaped Pulses, Pulsed Field Gradients, and Spin Locks—Selective 1D NOE and 1D TOCSY
  • Two-Dimensional NMR Spectroscopy—HETCOR, COSY, and TOCSY
  • Advanced NMR Theory—NOESY and DQF-COSY
  • Inverse Heteronuclear 2D Experiments—HSQC, HMQC, and HMBC
  • Biological NMR Spectroscopy
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