Upstream Processing
Everyone
- 11 videos | 55m 51s
- Includes Assessment
Learn about upstream processing in biomanufacturing
WHAT YOU WILL LEARN
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Understand the basics of upstream processingUnderstand how to calculate yieldUndestand the principles of cultivationUnderstand how bioreactors support cellular metabolismUnderstand bioreactor design featuresUnderstand the parts of a bioreactor
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Understand the parts of a bioreactorUnderstand the principles of oxygen transferUnderstand the principles of mechanical agitationUnderstand how to calculate shear stressUnderstand how wave reactors work
IN THIS COURSE
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5m 20sIn the following video, Professor Love will discuss upstream processing concepts in more detail and explain the fundamentals of cultivating cells for the production of biologic drugs. FREE ACCESS
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7m 31sIn the following tablet capture segment, Nicholas Mozdzierz, graduate student in the Department of Chemical Engineering at MIT, guides you through a sample problem focusing on upstream process yield. FREE ACCESS
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6m 31sIn the following video, Professor Love discusses cultivation topics in more detail. FREE ACCESS
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4m 47sAs you learned in the previous section, a bioreactor must provide the necessary raw materials to support cellular metabolism. In the following video, Professor Love will discuss this topic in more detail. FREE ACCESS
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2m 55sIn the following video, Professor Love will discuss how you design a bioreactor to supply nutrients & oxygen, remove byproducts, and maintain a uniform environment, all to support cellular metabolism and the… FREE ACCESS
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4m 45sNow that we've covered the different pieces of a bioreactor, it's time to see what one looks like in action. In the following video, Professor Love takes a field trip to Biogen. There, he is shown all of the… FREE ACCESS
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3m 8sYou've just seen most of the components of a bench-top bioreactor. In the following video, Professor Love finishes his field trip to Biogen. His guide, Senior Engineer Alan Gilbert, shows him the tubing used to add… FREE ACCESS
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6m 10sIn the following video, Professor Love discusses the principles of oxygen transfer in more detail. Understanding this will help you design a bioreactor and determine operating conditions that support cell growth and allow… FREE ACCESS
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5m 8sIn the following video, Professor Love discusses these impeller designs in more detail and talks about their advantages and disadvantages for cell culture. FREE ACCESS
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6m 32sIn the following tablet capture segment, Nicholas Mozdzierz, a graduate student in the Department of Chemical Engineering at MIT, guides you through a sample problem focusing on shear stress. FREE ACCESS
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3m 3sIn the following video, Professor Love visits Pfizer's Pilot Plant in Andover, MA. While there, he talks with John Coyne about the WAVE Bioreactor. FREE ACCESS